The bulk of your costs will stem from annual card fees and interest rates. You'll also want to watch out for punitive fees, which can add up if you are not careful.

For businesses that pay off their balance in full each month, annual card fees may be the most expensive part of owning a business card. On average, card fees range from $20 to $65 per card.

If your company expects to carry over a hefty balance each billing period, finding a business card with a low interest rate is absolutely essential. Currently, business card interest rates range from 14-19%.

Card issuers often offer several different interest rates to companies, depending on such factors as credit history, number of banking relationships, and spending volume. As a result, it pays not only to research interest rates for a number of different cards, but also to inquire about whether your company could qualify for one of the lower rates offered by the same card issuer.